Benfotiamine, Mega Benfotiamine

Benfotiamine, a fat-soluble form of vitamin B1 (thiamine), supports healthy blood sugar metabolism and helps protect the body's tissues against advanced glycation end products and oxidative stress. For example, the enzyme transketolase is critical to blood sugar metabolism. Like many enzymes, transketolase requires a co-factor. In this case, it needs assistance from thiamine. Unfortunately, thiamine is water-soluble, which makes it less available to the interior of the cell. Benfotiamine is fat-soluble and can easily penetrate into the inside of cells. It is also more bioavailable than the water-soluble thiamine.

In a landmark study, benfotiamine effectively increased transketolase activity in cell cultures by an astounding 300%, compared to a mere 20% for thiamine. This robust activation was sufficient to block three of the four major metabolic pathways leading to blood vessel damage. Benfotiamine also blocks the activation of the transcription factor known as nuclear factor-kappa B (NF-kB), which is implicated in numerous inflammatory conditions.

Overall, benfotiamine can activate glucose metabolism and promote healthy blood glucose levels in those already within normal range. It can also reduce formation of advanced glycation end products to prevent glucose toxicity and correct endothelial cell defects caused by high concentrations of blood glucose, especially inside endothelial, retinal, kidney and nerve cells. Benfotiamine also helps maintain healthy endothelial function. Benfotiamine with Thiamine is a low-cost dietary supplement that can help maintain blood sugar levels in those already within within normal range and support the health of the nerves, kidneys, eyes, blood vessels, and heart.

Information provided by Life Extension Foundation

Benfotiamine's benefits include the following:

• Helps to improve overall energy by maintaining healthy levels of glucose and leptin
• Helps support immune health and function
• Acts as an antioxidant to protect tissues from free radical damage caused by AGEs
• Demonstrated to significantly support nerve health and conduction
• Helps to support a healthy heart
• Aids optimal vision and eye health
• Helps support healthy, balanced blood sugar
• Enhances and supports kidney health
• Aids in maintaining optimal digestion
• Helps to enhance and support healthy, balanced moods

DIRECTIONS: Take one to four capsule(s) daily with or without food, or as recommended by a healthcare practitioner.

Other Ingredients: vegetable cellulose (capsule), microcrystalline cellulose, dicalcium phosphate, rice flour, vegetable stearate, silica.

Contains rice.

This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, or corn. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.

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