Lumbrokinase, Fibrenase III

Lumbrokinase is an enzyme derived from Lumbricus rubellus (earthworms). Lumbricus rubellus has been used for centuries in the Far East as a traditional medicine. The earthworm's ability to break down fibrin (a fibrous protein involved in the clotting of blood) was reported in the 1920's. Since then, scientists in Japan have succeeded in extracting a fibrin dissolving enzyme consisting of six proteolytic (protein digesting) enzymes, which are collectively named Lumbrokinase. Lumbrokinase has proven valuable in acute, sub-acute, and chronic conditions associated with clotting tendencies and poor circulation.

Research has shown lumbrokinase to support the body in breaking up and dissolving the unhealthy coagulation of blood and to enhance fibrinolytic activity (the ability of some proteolytic enzymes to dissolve the fibrin in blood clots facilitating wound healing)

Lumbrokinase may have a significant effect in the prevention and treatment of:

• Ischemic (localized tissue anemia due to obstruction of the inflow of arterial blood) cerebrovascular disease
• Myocardiac infarction
• Vascular sudden deafness
• Retinal artery and vein occlusion induced blindness
• Pulmonary infarction

It is a good adjunctive treatment for patients who are on or have had EDTA chelation therapy or hyperbaric oxygen therapy

Lumbrokinase is easily taken, has few side effects and no hemorrhage risk. Since Lumbrokinase has no gastrointestinal reaction, it can be used as a substitute for patients who are unable to tolerate aspirin.

Lumbrokinase is also used in the prevention and treatment of hypercoagulability(the propensity to develop thrombosis (blood clots) due to an abnormality in the system of coagulation)associated with some chronic diseases, for example:

• Diabetes mellitus
• Pulmonary heart disease
• Atrial fibrillation
• Malignant tumor
• Systemic lupus erythematosus (is a chronic autoimmune connective tissue disease that can affect any part of the body. As occurs in other autoimmune diseases, the immune system attacks the body's cells and tissue, resulting in inflammation and tissue damage).
• Polycythemia vera (also known as "Erythremia" is a blood disorder in which the bone marrow makes too many red blood cells).
• Thrombocythemia (is a disorder in which excess platelets are produced, leading to abnormal blood clotting or bleeding).
• Glomerulonephritis (Inflammation of glomerulus. The glomerulus is part of a nephron, which in turn is the basic functional (working) unit of a kidney. Millions of nephrons acting together filter the blood to produce urine).
• Hemolytic anemia (Anemia caused by excessive destruction of red blood cells.
• Liver disease
• Preeclampsia (A toxic condition developing in the last 4 or 5 months of pregnancy that is characterized by a sudden rise in blood pressure, excessive weight gain, generalized edema (especially hands, ankles, feet and face), albuminuria, severe headache, and visual disturbances)

Being an unique oral anticoagulant and thrombolytic drug that possesses urokinase and t-PA activities, Lumbrokinase can be applied in a combined treatment for thrombosis disease with other anticoagulant medicine.

DIRECTIONS: As a dietary supplement, 1 capsule in the morning, 1 capsule in the afternoon and 2 capsules at bedtime, or as directed by a healthcare practitioner. May be taken with or without food. Take with 8-10 oz of water.

Contraindications: If taken with anticoagulant drugs use under medical supervision. Contraindicated in any conditions associated with bleeding.

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These statements have not been evaluated by the U.S.Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.